• Treat: prednisolone acetate 1% q1–2h with taper, cycloplegic (cyclopentolate/homatropine) to relieve pain and prevent synechiae.
• Work-up for recurrent, bilateral, granulomatous or posterior involvement: HLA-B27, syphilis (treponemal), TB (QuantiFERON), sarcoid (ACE/lysozyme, chest imaging).

Mnemonic for HLA-B27: ankylosing spondylitis, reactive arthritis, IBD, psoriatic arthritis — typically unilateral alternating acute anterior uveitis with fibrin/hypopyon.